Quinoline derivatives as leukotriene antagonists

Details Quinoline derivatives as leukotriene antagonists Quinoline derivatives as leukotriene antagonists

C - Chemistry, Metallurgy

07

D

C07D 215/02 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 215/18 (2006.01) C07D 401/02 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2163244

Compounds having formula (I) are antagonists of the actions of leukotrienes. These compounds an useful as anti-asthmatic, anti- allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

Des composés selon la formule (I) sont des antagonistes des actions des leucotriènes. Ces composés sont utiles en tant qu'agents anti-asthmatiques, anti-allergiques, anti-inflammatoires et cytoprotecteurs. Ils sont également utiles dans le traitement de l'angine, du spasme cérébral, de la néphrite glomérulaire, de l'hépatite, de l'endotoxémie, de l'uvéite et du rejet allogreffe.

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