Quinoline derivatives as pde iv and/or tnf inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 215/26 (2006.01) A61K 31/47 (2006.01)

Patent

CA 2289100

Compounds of formula (i) wherein R1 represents C1-6 alkoxy (alkyl portion optionally substituted with one or more halogens) or thioalkyl; Q represents an aryl or heteroaryl ring, attached through any appropriate atom and optionally substituted at any position(s) with one or more substituents R5. The compounds can be used to treat disease states, for example disease states associated with proteins that mediate cellular activity, for example by inhibiting tumour necrosis factor and/or by inhibiting phosphodiesterase IV.

L'invention concerne des composés de la formule (i) dans laquelle R¿1? représente un C¿1-6?alcoxy (la partie alkyle étant éventuellement substituée par un ou plusieurs halogènes) ou un thioalkyle; Q représente une chaîne aryle ou hétéroaryle liée à n'importe quel atome approprié et éventuellement substituée au niveau de n'importe quelle(s) position(s) par un ou plusieurs substituants R¿5?. Ces composés peuvent être utilisés pour traiter des états pathologiques, par exemple des états pathologiques associés à des protéines qui agissent sur l'activité cellulaire, par exemple, en inhibant le facteur de nécrose tumorale et/ou la phosphodiestérase IV.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Quinoline derivatives as pde iv and/or tnf inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Quinoline derivatives as pde iv and/or tnf inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinoline derivatives as pde iv and/or tnf inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1436594

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.