Quinoline derivatives useful in the treatment of mglur5...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 215/42 (2006.01) A61K 31/4706 (2006.01) A61K 31/4709 (2006.01) A61K 31/4741 (2006.01) A61P 25/00 (2006.01) C07D 405/12 (2006.01) C07D 491/056 (2006.01) C07D 491/113 (2006.01)

Patent

CA 2629991

Compounds of formula (I): and/or enantiomers and/or racemates and/or diastereomers and/or pharmaceutically acceptable salts thereof formed with acids or bases, to the process for their preparation, to the intermediates of the preparation process, to the pharmaceutical formulations containing these compounds and to their use in the prevention and/or treatment of mGluR5 receptor-mediated disorders.

La présente invention concerne des composés de formule (I) et/ou leurs énantiomères et/ou racémates et/ou diastéréomères et/ou sels pharmaceutiquement acceptables formés avec des acides ou des bases. L'invention concerne également leur procédé de préparation, les intermédiaires de ce procédé de préparation, les formulations pharmaceutiques contenant ces composés et leur utilisation dans la prévention et/ou le traitement des pathologies liées aux récepteurs mglur5.

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