C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 215/38 (2006.01) A61K 31/47 (2006.01) A61P 29/00 (2006.01) C07D 215/60 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 491/10 (2006.01)
Patent
CA 2514940
This invention is directed to vanilloid receptor VR1 ligands of formula (I). More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
L'invention concerne également des ligands VR1 du récepteur des vanilloïdes. L'invention concerne plus particulièrement des amides dérivés quinoliniques constituant de puissants antagonistes ou agonistes de VR1 qui conviennent au traitement et à la prévention d'états inflammatoires ou autrement pathologiques affectant des mammifères.
Codd Ellen
Dax Scott L.
Jetter Michele
Mcdonnell Mark
Mcnally James J.
Janssen Pharmaceutica N.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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