Quinoline quinazoline pyridine and pyrimidine compounds and...

C - Chemistry – Metallurgy – 07 – D

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C07D 417/00 (2006.01) A61K 31/47 (2006.01) C07D 401/12 (2006.01)

Patent

CA 2553433

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Des composés sélectionnés sont efficaces dans le cadre de la prophylaxie et du traitement de maladies, telles que les maladies induites par le facteur de croissance des hépatocytes (HGF). Cette invention concerne de nouveaux composés, des analogues, des promédicaments et des sels pharmaceutiquement acceptables de ces derniers et des méthodes de prophylaxie et de traitement de maladies et d'autres pathologies ou états tels que le cancer et autres. Cette invention se rapporte également à des procédés de préparation de tels composés ainsi qu'à des intermédiaires utiles dans de tels procédés.

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