Quinolinecarboxylic acid derivatives and antibacterial agent...

C - Chemistry – Metallurgy – 07 – D

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167/211, 260/246

C07D 513/16 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01)

Patent

CA 2012063

- 86 - Abstract of the Disclosure: QUINOLINECARBOXYLIC ACID DERIVATIVES AND ANTIBACTERIAL AGENT CONTAINING THE SAME Novel quinolinecarboxylic acid derivatives of the formula: Image (I) wherein Z is Image or Image in which R1 and R2 are each hydrogen atom or a lower alkyl, R3 is hydrogen atom, hydroxy or a lower alkyl and R4 is hydrogen atom, hydroxy, amino, aminomethyl, a (lower alkyl)aminomethyl or a di(lower alkyl)aminomethyl, and a pharmaceutically acceptable salt thereof. The compounds have excellent antibacterial activities and are useful as an antibacterial agent.

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