Quinolines as inhibitors of farnesyl pyrophosphate synthase

Details Quinolines as inhibitors of farnesyl pyrophosphate synthase Quinolines as inhibitors of farnesyl pyrophosphate synthase

C - Chemistry, Metallurgy

07

D

C07D 215/48 (2006.01) A61K 31/675 (2006.01) A61P 35/04 (2006.01) C07D 215/18 (2006.01) C07D 401/04 (2006.01) C07D 409/04 (2006.01) C07D 409/14 (2006.01) C07D 417/12 (2006.01) C07F 9/60 (2006.01)

Patent

CA 2717011

The invention relates to a compound of formula (I) wherein the substituents are as described in the specification, which are useful as farnesyl pyrophosphate synthase modulators, e.g. in the treatment of proliferative diseases, to methods of manufacturing such compounds and to intermediates thereof.

Linvention porte sur un composé de formule (I), dans laquelle les substituants sont tels que décrits dans la description, qui sont utiles en tant que modulateurs de la farnésyl pyrophosphate synthase, par exemple dans le traitement de maladies prolifératives, sur des procédés de fabrication de tels composés et sur des intermédiaires de ceuxci.

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