Quinolinone compounds as 5-ht4 receptor agonists

C - Chemistry – Metallurgy – 07 – D

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C07D 451/04 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01) A61K 31/5355 (2006.01) A61K 31/541 (2006.01) A61P 1/00 (2006.01)

Patent

CA 2599404

The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5 HT4 receptor activity, and processes and intermediates useful for preparing such compounds.

L~invention concerne de nouveaux composés agonistes des récepteurs 5-HT4 de quinolinone-carboxamide. Cette invention a trait également aux compositions pharmaceutiques contenant ces composés, aux méthodes d~utilisation de ces composés afin de traiter des maladies associées à l~activité du récepteur 5 HT4, ainsi qu~aux procédés et intermédiaires utiles dans la préparation de ces composés.

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