A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4704 (2006.01) A61K 9/14 (2006.01) A61K 47/38 (2006.01) A61P 37/08 (2006.01)
Patent
CA 2390746
A quinolinone derivative pharmaceutical composition comprising a quinolinone derivative represented by the structural formula (I): (see formula I) wherein the quinolinone derivative is in the form of particles, which have an average particle diameter of 0.5 to µm and such a particle size distribution that particles having a particle diameter of 15 µm or less account for 90% or more of the totality of the particles, and also have a fusion enthalpy of 30 J/g or more, and the surface of the particles are coated with a water-soluble composition containing a water-soluble polymer, can quickly dissolve an active ingredient in the digestive tract and is also superior in long-term storage stability.
Araya Hiroshi
Fukui Hiroyuki
Kimura Nobuyuki
Kubota Ryuji
Obata Kouki
Dainippon Ink And Chemicals Inc.
Kirby Eades Gale Baker
Mariposa Health Limited
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