Quinolinyl-benzopyran derivatives as antagonists of...

C - Chemistry – Metallurgy – 07 – D

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C07D 215/00 (2006.01) A61K 31/47 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)

Patent

CA 2036381

ABSTRACT OF THE DISCLOSURE The present application is concerned with novel quinolinyl-benzopyran derivatives of the general formula: Image and compositions thereof. The compounds of the present invention have LTD4 antagonist properties, and are therefore particularly useful for treating disorders which result from LTD4 activity, such as inflammatory conditions and allergic responses. Preferred compounds of the invention possess dual activity as mediator re- lease inhibitors and LTD4 antagonists.

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