C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4709 (2006.01) A61P 31/04 (2006.01)
Patent
CA 2408806
(-)-7-[(7S)-7-Amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1- cyclopropyl]-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic acid monohydrochloride monohydrate and antibacterial agents containing the same. This compound is excellent in antibacterial activity and safety and highly stable to light and humidity, which makes it useful as an antibacterial agent.
L'invention concerne un monohydrate de monochlorhydrate d'acide (-)-7-[7(S)-7-Amino-5-azapiro[2,4]heptane-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-1,4-dihydro-8-méthoxy-4-oxo-3-quinoléine-carboxylique et des agents antibactériens le contenant. Ce composé présente une activité antibactérienne et une innocuité élevées, ainsi qu'une haute stabilité à la lumière et à l'humidité, d'où son utilité comme agent antibactérien.
Hayakawa Isao
Itoh Masao
Kawakami Katsuhiro
Miyauchi Rie
Ohtani Tsuyoshi
Daiichi Pharmaceutical Co. Ltd.
Gowling Lafleur Henderson Llp
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