Quinolonecarboxylic acid derivatives

Details Quinolonecarboxylic acid derivatives Quinolonecarboxylic acid derivatives

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) C07D 215/56 (2006.01)

Patent

CA 2114981

ABSTRACT Presented is a novel quinolonecarboxylic acid derivative of the formula I and its pharmaceutically acceptable salt: Image (I) wherein R1 is hydrogen, halogen or lower alkoxy, R2 is hydrogen, lower alkyl, lower alkoxy, -NH2, -NHCOCH, or halogen, R3 is lower alkyl, and z is a group represented by the formula II or III: Image (II) (III) wherein R4 and R5 are identical or different and are hydrogen or lower alkyl. A method of preparation of these compound and a method of treatment of diseases caused by bacterial infection are also presented.

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