Quinolones as serine protease inhibitors

Details Quinolones as serine protease inhibitors Quinolones as serine protease inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/06 (2006.01) A61K 31/44 (2006.01) A61K 31/47 (2006.01) C07D 215/227 (2006.01) C07D 401/14 (2006.01) C07D 403/06 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2312953

This invention discloses quinolinones which display inhibitory effects on serine proteases such as factor Xa, thrombin and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable compositions comprising the compounds, their salts or prodrugs, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.

L'invention concerne des composés de quinolinones qui ont des effets inhibiteurs sur des sérines-protéases telles que le facteur Xa, la thrombine et le facteur VIIa. L'invention concerne également des sels et des promédicaments pharmaceutiquement acceptables de ces composés, des compositions pharmaceutiquement acceptables contenant ces composés, leurs sels ou leurs promédicaments, ainsi que des méthodes pour les utiliser comme agents thérapeutiques pour traiter ou prévenir chez des mammifères des états pathologiques caractérisés par une thrombose anormale.

Affiliated with

Also associated with

Rating

Quinolones as serine protease inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Quinolones as serine protease inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinolones as serine protease inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1817220