Quinone amides, their production and use

Details Quinone amides, their production and use Quinone amides, their production and use

C - Chemistry, Metallurgy

07

C

167/179, 260/253

C07C 235/78 (2006.01) C07D 239/95 (2006.01) C07D 295/185 (2006.01) C07D 307/68 (2006.01) C07D 403/06 (2006.01) C07H 19/16 (2006.01)

Patent

CA 1307259

Abstract of the disclosure Compounds of the formula: Image (wherein R1 is an optionally substituted phenyl group, R2 is an optionally substituted amino group and n is an integer of 3 to 10) or a hydroquinone derivatives thereof are novel compounds, possess metabolism ameliorating action for poly unsaturated fatty acids, particularly production inhibitory activity of lipid peroxides, production inhibitory activity of 5-lipoxygenase metabolites, inhibitory actions of lenkotrienes or platelet aggregating factor-induced bronchoconstrictions and scavenging action of activated oxygen species, and are useful as drugs such as antiasthmatic, antiallergic agent and therapeutic and ameliorating agent for cadiac-, cerebral- and renal-circulatory disorders.

528211

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