Quinone derivatives

Details Quinone derivatives Quinone derivatives

C - Chemistry, Metallurgy

07

D

C07D 213/55 (2006.01) A61K 31/415 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) C07D 213/56 (2006.01) C07D 233/60 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 413/06 (2006.01)

Patent

CA 2062263

ABSTRACT OF THE DISCLOSURE Quinone derivatives exhibiting excellent pharmacological activity are disclosed. The quinone derivatives are represented by the general formula: Image (I) wherein A stands for a group represented by the formula: Image (wherein R3, R4 and R5 are the same or different from each other and each stands for a hydrogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, an alkoxyalkyl group, an alkoxyalkoxy group, a cycloalkylalkoxy group, a thiol group or a thioalkyl group, with the proviso that R3 and R4 are not both a lower alkoxy group) or a group represented by the formula: Image (wherein R3, R4 and R5 are the same or different from each other and each stands for a hydrogen atom, a hydroxyl group, a lower alkyl group, a lower alkoxy group, an alkoxyalkyl group, an alkoxyalkoxy group, a cycloalkylalkoxy group, a thiol group or a thioalkyl group, with the proviso that R3 and R4 are not both a lower alkoxy group; and X and Y are the same or different from each other and each stands for a hydroxyl group or a protected hydroxyl group); R1 stands for a heteroarylalkyl group and B stands for a carboxyl group or a protected carboxyl group, and pharmacologically acceptable salts thereof.

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