Quinoxaline-containing compounds as hepatitis c virus...

C - Chemistry – Metallurgy – 07 – D

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D 498/18 (2006.01) A61K 31/4995 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2705807

The present invention discloses compounds of formula I and II or pharmaceutically acceptable salts, esters, or prodrugs thereof which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

La présente invention concerne des composés de formule I et II ou des sels pharmaceutiquement acceptables de ceux-ci, des esters, ou des promédicaments de ceux-ci qui inhibent l'activité de la sérine protéase, en particulier l'activité de la protéase NS3-NS4A du virus de l'hépatite C (VHC). En conséquence, les composés de la présente invention interfèrent avec le cycle de vie du virus de l'hépatite C et sont également utiles en tant qu'agents antiviraux. La présente invention concerne en outre des compositions pharmaceutiques comprenant les composés mentionnés ci-dessus pour l'administration à un sujet souffrant d'une infection par le VHC. L'invention concerne également des procédés de traitement d'une infection par le VHC chez un sujet en administrant une composition pharmaceutique comprenant les composés de la présente invention.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Quinoxaline-containing compounds as hepatitis c virus... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Quinoxaline-containing compounds as hepatitis c virus..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Quinoxaline-containing compounds as hepatitis c virus... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1466569

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.