C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 241/44 (2006.01) A61K 31/498 (2006.01) A61P 3/10 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01)
Patent
CA 2717718
The present invention relates to quinoxalinone derivatives of formula (I), wherein R1, R2, R3, R4, R5 and R6 are as defined in claim 1, as insulin secretion stimulators. The invention also relates to the preparation and use of these quinoxalinone derivatives for the prophylaxis and/or treatment of diabetes and pathologies associated. Other preferred compounds are compounds of general formula (I), wherein R1, R2, R3, R4, R5 and R6 can be optionally substituted by one or more groups selected from Z.
La présente invention concerne des dérivés de quinoxalinone de la formule (I), dans laquelle R1, R2, R3, R4, R5 et R6 sont tels que définis dans la revendication 1, comme stimulateurs de la sécrétion dinsuline. Linvention concerne également la préparation et lutilisation de ces dérivés de quinoxalinone pour la prophylaxie et/ou le traitement du diabète et des pathologies associées. Dautres composés préférés sont des composés de la formule générale (I), dans laquelle R1, R2, R3, R4, R5 et R6 peuvent être éventuellement substitués par un ou plusieurs groupes choisis parmi Z.
Botton Gerard
Charon Christine
Elbawab Samer
Kergoat Micheline
Valeur Eric
Fetherstonhaugh & Co.
Merck Patent Gmbh
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