Quinuclidine derivatives binding to mucarinic m3 receptors

Details Quinuclidine derivatives binding to mucarinic m3 receptors Quinuclidine derivatives binding to mucarinic m3 receptors

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/5365 (2006.01) A61P 11/06 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2523436

Compounds of formula (I), in salt or zwitterionic form wherein, wherein R1, R2, R3, and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by the muscarinic M3 receptor. Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

Cette invention concerne des composés représentés par la formule (I) sous forme de sel ou de composés zwitterioniques, dans laquelle R?1¿, R?2¿, R?3¿, et R?4¿ ont la signification indiquée dans le descriptif, convenant pour le traitement de manifestations induites par le récepteur muscarinique de type M3. Sont également décrites des compositions pharmaceutiques contenant lesdits composés et une méthode de préparation de ces composés.

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