Quinuclidine derivatives, processes for preparing them and...

Details Quinuclidine derivatives, processes for preparing them and... Quinuclidine derivatives, processes for preparing them and...

C - Chemistry, Metallurgy

07

D

C07D 453/02 (2006.01) A61K 31/439 (2006.01) A61P 13/02 (2006.01)

Patent

CA 2462980

The invention concerns quinuclidine derivatives of formula I or II wherein the substituents are as defined in the specification, as well as their use as pharmaceuticals. The compounds of the invention_show high affinities for m3 and/or m2 muscarinic receptors and are particularly suited for treating urinary incontinence.

L'invention concerne des dérivés de quinuclidine de formule I ou II dans laquelle les substituants ont la signification indiquée dans la description, ainsi que leur utilisation en tant que médicaments. Les composés de l'invention présentent de hautes affinités pour des récepteurs muscariniques m3 et/ou m2 et sont particulièrement appropriés au traitement de l'incontinence urinaire.

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