Quinuclidine-substituted heteroaromatic compounds as ligands...

C - Chemistry – Metallurgy – 07 – D

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C07D 453/02 (2006.01) A61K 31/439 (2006.01) C07D 519/00 (2006.01)

Patent

CA 2445471

The invention provides compounds of Formula (I): wherein W0 is a bicyclic moiety and is (I). These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful to treat diseases or conditions in which .alpha.7 is known to be involved.

La présente invention concerne des composés de la formule (1), dans laquelle W?0 ¿est un fragment bicyclique et est (1). Les composés de l'invention peuvent se présenter sous la forme de sels ou de compositions pharmaceutiques, sous une forme énantiomériquement pure ou sous la forme de mélanges racémiques, et ils sont utilisés pour traiter des maladies ou des états dans lesquels l'alpha7 est impliqué.

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