C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/21 (2006.01) C12N 15/78 (2006.01)
Patent
CA 2383743
The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention provides quorum sensing controlled genetic loci in (Pseudomas aeruginosa. Novel indicator strains and vectors for engineering the strains for use in the method of the invention are also provided.
L'invention concerne des procédés servant à identifier un modulateur de signalisation bactérienne désignée signalisation de détection de quorum, ainsi qu'à identifier un gène contrôlé de détection de quorum chez des bactéries. Elle concerne également des locus génétiques contrôlés de signalisation bactérienne ou de détection de quorum chez Pseudomonas aeruginosa. Elle concerne, de plus, de nouvelles souches et de nouveaux vecteurs d'indication servant à exécuter des opérations de génie génétique sur ces souches afin de les mettre en application dans le procédé décrit.
Greenberg E. Peter
Lee Kimberly M.
Muh Ute
Whiteley Marvin
Borden Ladner Gervais Llp
Quorum Sciences Inc.
The University Of Iowa Research Foundation
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