(r)-2-(4-amidinophenylaminomethyl)-1-methyl-5-(1-(carboxymet...

Details (r)-2-(4-amidinophenylaminomethyl)-1-methyl-5-(1-(carboxymet... (r)-2-(4-amidinophenylaminomethyl)-1-methyl-5-(1-(carboxymet...

C - Chemistry, Metallurgy

07

D

C07D 235/14 (2006.01) A61K 31/4184 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2485545

The invention relates to the crystalline forms of compounds (R)-2-(4- amidinophenylaminomethyl)-1-methyl-5-(1-(carboxymethylamino)-1- (pyrrolidinocarbonyl)-ethyl)-benzimidazole and monohydrochloride thereof, to methods for the production thereof, and to their use as medicaments having an antithrombotic action.

La présente invention concerne les formes cristallines des composés (R)-2-(4-amidinophénylaminométhyl)-1-méthyl-5-(1-(carboxyméthylamino)-1-(pyrrolidinocarbonyl)-éthyl)-benzimidazol et son monohydrochlorure, des procédés de production desdites substances et leur utilisation en tant que médicaments à action antithrombotique.

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