(r)-.alpha.-ethyl-2-oxo-l-pyrrolidineacetamide

Details (r)-.alpha.-ethyl-2-oxo-l-pyrrolidineacetamide (r)-.alpha.-ethyl-2-oxo-l-pyrrolidineacetamide

C - Chemistry, Metallurgy

07

D

260/324

C07D 207/27 (2006.01)

Patent

CA 1237138

ABSTRACT OF THE DISCLOSURE: The invention relates to (R)-alpha-ethyl-2-oxo-1- pyrrolidineacetamide of the formula: Image and to its preparation either by reacting (R)-alpha-ethyl-2- oxo-1-pyrrolidineacetic acid successively with an alkyl haloformate and with ammonia, or by cyclizing an (R)-2- amino-butanamide of the formula X-CH2CH2-Y-NHCH(C2H5)CONH2 wherein Y is a -CH2- radical when X represents a ZOOC- radical and Y is a -CO- radical when X represents a HalCH2- radical, Z being a C1-C4 alkyl radical and Hal a halogen atom. This dextrorotatory enantiomer has been found to have significantly higher mnemic activity and lower toxicity than the corresponding racemate.

481511

Affiliated with

Also associated with

Rating

(r)-.alpha.-ethyl-2-oxo-l-pyrrolidineacetamide does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with (r)-.alpha.-ethyl-2-oxo-l-pyrrolidineacetamide, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and (r)-.alpha.-ethyl-2-oxo-l-pyrrolidineacetamide will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1189907