R-n-(2-phenyl-2-hydroxyethyl)-3-phenylpropyl amines,...

C - Chemistry – Metallurgy – 07 – C

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260/602.3

C07C 215/54 (2006.01)

Patent

CA 1126296

X-4996 -1- ABSTRACT R-N-(2-Phenyl-2-hydroxyethyl)-3-phenyl- propylamines of formula (I): Image (I) wherein: R1 is hydrogen or fluorine; R2 is hydrogen or hydroxy; provided that at least one of R1 or R2 is hydrogen; R3 is hydroxy; C is an asymmetric carbon atom having the * R absolute stereochemical configuration; and phar- maceutically-acceptable salts thereof, can be used in the treatment of conditions of depressed cardiac contractility or to physically condition biological systems.

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