C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/62 (2006.01) A61K 31/215 (2006.01) A61K 31/375 (2006.01) C07C 69/612 (2006.01) C07C 69/614 (2006.01) C07C 69/616 (2006.01) C07D 405/04 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/12 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2501239
The present invention concerns esters of R-enantiomers of a non-steroidal anti- inflammatory drug, which is substantially free from the S-enantiomer. The compounds of the invention may be used in treating a disease or illness in a mammal. To this end, a composition comprising a compound mentioned above, or a pharmaceutically acceptable salt thereof where salt formation occurs, is administered to the mammal in an amount sufficient to elicit a chemopreventative effect or a chemoprotective effect or a therapeutic effect or a prophylactic effect.
La présente invention concerne des esters de R-énantiomères d'un anti-inflammatoire non-stéroïdien sensiblement exempt de S-énantiomère. Les composés de l'invention conviennent au traitement d'affections ou de maladies touchant un mammifère. A cet effet, on administre au mammifère considéré une composition comprenant un composé selon l'invention, ou l'un de ses sels pharmaceutiquement admis en cas de formation d'un sel, l'administration portant sur une quantité suffisante pour provoquer un effet chimiopréventif, chimioprotecteur, thérapeutique ou prophylactique.
Schwartz Elaine Benaksas
Wechter William J.
Encore Pharmaceuticals Inc.
Gowling Lafleur Henderson Llp
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