A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/40 (2006.01)
Patent
CA 2315840
A method for treating urinary incontinence, such as incontinence resulting from bladder detrusor muscle instability, using enantiomerically enriched (R)- procyclidine. The method comprises administering a therapeutically effective amount of enantiomerically enriched (R)-procyclidine, or a pharmaceutically acceptable salt thereof, substantially free of the (S)-procyclidine enantiomer. Pharmaceutical compositions for the treatment of urinary incontinence comprising enantiomerically enriched (R)-procyclidine, or a pharmaceutically acceptable salt thereof, and an acceptable carrier are also disclosed.
L'invention porte sur un procédé de traitement de l'incontinence urinaire telle que l'incontinence due à l'instabilité du muscle vésical de la vessie et utilisant (R)-procyclidine enrichie de façon énantiomère. Ce procédé consiste à administrer une quantité thérapeutiquement efficace de (R)-procyclidine enrichie de façon énantiomère, ou un sel pharmaceutiquement acceptable de celle-ci, pratiquement exempt de énantiomère (S)-procyclidine. L'invention porte également sur des compositions pharmaceutiques utilisées dans le traitement de l'incontinence urinaire et comprenant (R)-procyclidine enrichie de façon énantiomère, ou un sel pharmaceutiquement acceptable de celle-ci et un excipient acceptable.
Fabiano Vincent L.
Mccullough John R.
Borden Ladner Gervais Llp
Sepracor Inc.
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