Rabbit monoclonal antibodies to hepatitis b surface antigens...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/70 (2006.01) C07K 16/08 (2006.01)

Patent

CA 2569561

Reagents, methods and immunodiagnostic test kits for the accurate detection of hepatitis B virus (HBV) infection are disclosed. The methods and kits employ novel rabbit monoclonal antibodies directed against HBV surface antigens (HBsAg) with mutations in the "a" determinant region of HBsAg.

Réactifs, procédés, kits de tests immunodiagnostiques pour la détection précise de l'infection par le virus de l'hépatite B (VHB). Procédés et kits reposent sur l'utilisation d'anticorps monoclonaux de lapin vis-à-vis des antigènes de surface du VHB (HBsAg) avec des mutations dans la zone <= a >= déterminante des HBsAg.

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