Rabbit single domain antibody and use thereof

Details Rabbit single domain antibody and use thereof Rabbit single domain antibody and use thereof

C - Chemistry, Metallurgy

07

K

C07K 16/40 (2006.01) C07K 16/00 (2006.01) G01N 33/543 (2006.01) G01N 33/545 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2114720

2114720 9325686 PCTABS00028 In accordance with the present invention, there is provided a recombinant rabbit heavy chain variable domain, or single domain antibody having the ability to bind to a solid phase, for example, plastic, without a decrease in antigen capture capacity. The present invention further provides an improved immunological sandwich assay, such as an ELISA, in which the rabbit single domain antibody of the present invention is directly bound to the solid phase as the capture antibody. The resulting assay is less complex than systems currently utilized without any decrease in sensitivity.

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