C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 39/42 (2006.01) A61P 31/14 (2006.01) C07K 16/10 (2006.01) C12N 5/20 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2419148
Human monoclonal rabies virus neutralizing antibodies represent a safe and efficacious post-exposure prophylactic therapy for individuals exposed to a rabies virus. The nucleic acid and encoded amino acid sequences of the heavy and light chain immunoglobulins of human monoclonal rabies virus neutralizing antibodies, and their use, is described.
L'utilisation d'anticorps monoclonaux humains neutralisant le virus de la rage représente un traitement prophylactique post-exposition efficace pour les sujets exposés à un virus de la rage. L'invention porte également sur un acide nucléique et les séquences d'acides aminés codées des immunoglobulines à chaîne lourde et légère d'anticorps monoclonaux humains neutralisant le virus de la rage, ainsi que sur leur utilisation.
Dietzschold Bernhard
Hooper Douglas C.
Borden Ladner Gervais Llp
Thomas Jefferson University
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