C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/867 (2006.01)
Patent
CA 2624768
Rabies Virus compositions and methods are provided. The full-length sequence of Rabies Virus strain Evelyn-Rokitnicki-Abelseth (ERA) is disclosed. A reverse genetics system for producing recombinant ERA virus and derivatives thereof is provided, along with compositions including ERA and/or ERA derivative strain viruses, nucleic acids and/or proteins. In some instances, the compositions are immunogenic compositions useful for the pre- or post- exposure treatement of Rabies Virus.
La présente invention concerne des compositions et des procédés contre des virus rabiques. L~invention porte aussi sur la séquence complète de la souche de virus rabique Evelyn-Rokitnicki-Abelseth (ERA). L~invention concerne aussi un système génétique inverse permettant de produire un virus ERA recombinant et ses dérivés, ainsi que des compositions comprenant des virus de souche ERA et/ou dérivée de ERA, des acides nucléiques et/ou des protéines. Dans certaines circonstances, les compositions sont des compositions immunogènes utiles pour le traitement pré- ou post-exposition au virus rabique.
Rupprecht Charles E.
Wu Xianfu
Smart & Biggar
The Government Of The United States Of America As Represented By Centers For Disea
LandOfFree
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