Raccoon poxvirus expressing genes of porcine virus

Details Raccoon poxvirus expressing genes of porcine virus Raccoon poxvirus expressing genes of porcine virus

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01)

Patent

CA 2687026

The present invention relates to a new recombinant raccoon poxvirus vector vaccine in which the vector expresses one or more antigenic proteins encoded by multiple open reading frames, preferably the ORF5, ORF6 and/or ORF3/ORF4/ORF7, of one or more porcine reproductive and respiratory syndrome virus strains alone or in combination with an open reading frame of porcine circovirus type 2 (PCV-2), preferably ORF2, at the hemagglutinin (ha) and/or thymidine kinase (tk) loci.

La présente invention concerne un nouveau vaccin à vecteur poxvirus de raton laveur recombinant dans lequel le vecteur exprime une ou plusieurs protéines antigéniques codées par plusieurs cadres ouverts de lecture, de préférence ORF5, ORF6 et/ou ORF3/ORF4/ORF7, d'une ou de plusieurs souches de virus du syndrome dysgénésique et respiratoire du porc, seuls ou combinés à un cadre ouvert de lecture d'un circovirus porcin de type 2 (PCV-2), de préférence ORF2, au niveau du site de l'hémagglutinine (ha) et/ou de la thymidine (tk).

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