C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/60 (2006.01) C07B 53/00 (2006.01) C07B 55/00 (2006.01)
Patent
CA 2200490
A process for the racemisation of an optically-enriched piperidine-2- carboxanilide compound, comprises hearing the compound in the presence of an alkanoic or arylalkanoic acid. A process for the asymmetric transformation of such a compound comprises heating the compound in the presence of an acid as defined above, a chiral acid resolving agent and an inert cosolvent.
Procédé d'obtention de racémiques à partir d'un composé de pipéridine-2-carboxanilide, enrichi optiquement, consistant à réchauffer ce composé en présence d'un acide alcanoïque ou d'un acide arylalcanoïque. L'invention porte également sur un procédé de transformation asymétrique dudit composé, consistant à réchauffer celui-ci en présence d'un acide comme susmentionné, d'un agent dissolvant d'acide chiral et d'un co-solvant inerte.
Dyer Ulrich Conrad
Lock Christopher James
Woods Martin
Borden Ladner Gervais Llp
Chiroscience Limited
Darwin Discovery Limited
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