Racemization of optically active amines

Details Racemization of optically active amines Racemization of optically active amines

C - Chemistry, Metallurgy

07

C

C07C 211/29 (2006.01) C07C 209/00 (2006.01) C07C 209/62 (2006.01) C07C 209/86 (2006.01) C07C 213/10 (2006.01) C07C 217/58 (2006.01) C07C 253/34 (2006.01) C07C 255/58 (2006.01) C07C 319/28 (2006.01) C07C 323/32 (2006.01)

Patent

CA 2197900

A process for the racemization of optically active amines of the formula (I), where Ar is an unsubstituted or substituted aryl and R is alkyl, in which a) (I) is reacted with the ketone (II) in which Ar and R have the same meanings as for (I), to give the condensation product (III), (see formulas I, II, III) b) (III) is racemized by treatment with base, (see formula III) c) the arylalkylamine (I) is liberated as racemate from racemic (III) by reaction with optically active (I). (see formula I) (see formula III)

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