Radio labeled dihematoporphyrin ether and its use in...

Details Radio labeled dihematoporphyrin ether and its use in... Radio labeled dihematoporphyrin ether and its use in...

C - Chemistry, Metallurgy

07

D

167/47, 260/237.

C07D 519/00 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1337986

Radiolabeled dihematoporphyrin ether having the following general formula Image wherein at least one of R1-R6 is a moiety labeled with a radionuclide imaging agent is useful in providing a non-invasive nuclear scintillation image. This dihematoporphyrin ether localizes in neoplastic tissue and thus provides a method of imaging and recording the location of neoplastic tissue. When the labeling agent has an adequate component of particulate radiation, the dihematoporphyrin ether can be used as a therapeutic agent as well as a diagnostic imaging agent.

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