Radioactive complex for diagnostic visualization of...

A - Human Necessities – 61 – K

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A61K 49/00 (2006.01) A61K 51/04 (2006.01)

Patent

CA 1057655

A B S T R A C T This invention relates to a preparation for the diagnostic visuali- zation of neoplastic tissues, i.e. tumors and metastases, by means of tissue scintigraphy. The preparation of this invention consists essentially of an injectable complex of 99mTechnetium or IIIIndium with a dicarboxylic or tri- carboxylic acid of the general formula Image in which n is 1 or 2, R1 and R2 together are an oxygen atom or the ?CH-COOH group or R1 is a hydrogen atom or a hydroxyl or amino group and R2 is a hydro- gen atom or one of the following groups: -CH2-COOH -CHOH-COOH -CO-COOH, or with a water soluble salt of the same, in sterile aqueous solution having a physiologically harmless pH value.

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