Radioactive diagnostic agent and non-radioactive carrier...

Details Radioactive diagnostic agent and non-radioactive carrier... Radioactive diagnostic agent and non-radioactive carrier...

A - Human Necessities

61

K

167/159, 167/48

A61K 47/00 (2006.01) A61K 49/00 (2006.01) A61K 51/04 (2006.01) C07D 213/66 (2006.01)

Patent

CA 1186624

- 1 - Abstract: The invention relates to a 99mTc-labeled radioactive diagnostic agent useful for visualization and dynamic inspection of hepatobiliary ducts and having a high stability and no significant toxicity. The diagnostic agent comprises 99mTc in the form of a pertechnetate and a non-radioactive carrier, the non-radioactive carrier comprising an N-pyridoxyl-.alpha.-amino acid of the formula: Image wherein R1 and R2 are each an atom or an atomic group present in the a-amino acid residue encompassed by the dotted line and R3, R4, R5 and R6 are each a hydrogen atom, a halogen atom, a Cl-C10 alkyl group or a C1-C10 alkyl group substituted with at least one hydrophilic group or its salt, and a reducing agent for the pertechnetate.

390956

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