Radioactive iodine compound for labeling an antibody

Details Radioactive iodine compound for labeling an antibody Radioactive iodine compound for labeling an antibody

C - Chemistry, Metallurgy

07

D

C07D 207/452 (2006.01) C07D 207/40 (2006.01) G01N 33/534 (2006.01) G01N 33/60 (2006.01)

Patent

CA 2056633

The radioactive iodine compound of this invention or an intermediate for preparing the compound is represented by the following formula (I): (see formula I) wherein R is H or 125I. The radioactive compound can readily intro- duce a radioactive isotope element such as 125I into an antibody molecule without damaging the activity of the antibody molecule. Therefore, the compound can prefera- bly be used to label an antibody of immunoradiometric assay, and allow a higher degree of measurement sensi- tivity.

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