A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/00 (2006.01) A61M 29/02 (2006.01) A61N 5/10 (2006.01) G21G 4/08 (2006.01)
Patent
CA 2470006
The present invention relates to a method for implantation of Xe isotopes in a matrix for production of 125I sources that do not shed radioactive atoms. 125Xe implanted at 12kV in steel, titanium and gold does not evol ve after more than 10 half-lives (380h) and 125I from the decay of implanted 125Xe is equally stable for 2 half-lives (120d). The matrix having radioxenon implanted is useful as a medical device, for instance as a "seed" for radiotherapeutic uses or in production of stents. Methods of treatment utilizing such devices are also encompassed by the present invention.
L'invention concerne un procédé d'implantation d'isotopes Xe, dans une matrice destinée à la production de source <sp>125</sp>I n'excrétant pas d'atomes radioactifs. Le <sp>125</sp>Xe implanté à 12kV dans l'acier, le titane et l'or n'évoluent pas après plus de 10 demi-vies (380h) et la <sp>125</sp>I issue de la pourriture de <sp>125</sp>Xe implanté est également stable pour 2 demi-vies (120d). La matrice possédant du radioxénon implanté est utile en tant que dispositif médical, notamment en tant que <=graine>= à usages radiothérapeutiques ou dans la production d'endoprothèses. L'invention concerne également des procédés de traitement utilisant ces dispositifs.
D'auria John Michael
Harshman Dale R.
Ottewell David F.
Ruth Thomas J.
Vincent John S.
Coll The University Of Alberta The University Of British Columbia Car
Sim & Mcburney
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