Radioactive metals complexed with derivatives of...

C - Chemistry – Metallurgy – 07 – F

Patent

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167/47, 260/428.

C07F 13/00 (2006.01) A61K 51/04 (2006.01) G01N 33/60 (2006.01)

Patent

CA 1232914

ABSTRACT New stable complexing agents for Tc-99m which are phosphonate derivatives of bicycloheptane bis(alkylamines) have been found which are useful in imaging the skeletal system in animals. The complexes readily clear through the kidneys with large amounts being taken up in the bone. The ratio of uptake in bone to that in soft tissue is high. 31,284-F

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