Radioactively-labeled somatostatin-derived peptides for...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/655 (2006.01) A61K 51/08 (2006.01) A61K 38/00 (2006.01) A61K 43/00 (1990.01) A61K 49/02 (1990.01)

Patent

CA 2138647

This invention relates to therapeutic reagents and peptides, radiodiagnostic reagents and peptides, and methods for produ- cing labeled radiodiagnostic agents. Specifically, the invention relates to peptide derivatives and analogs of somatostatin, and em- bodiments of such peptides labeled with technetium-99m (Tc-99m), as well as methods and kits for making, radiolabeling and us- ing such peptides to image sites in a mammalian body. The invention also relates to peptide derivatives and analogues of somatostantin labeled with rhenium-186(186Re) and rhenium-188(188Re), and methods and kits for making, radiolabeling and using such peptides therapeutically in a mammalian body.

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