Radiographic scanning agent

C - Chemistry – Metallurgy – 07 – F

Patent

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Details

260/428.1, 260/5

C07F 9/30 (2006.01)

Patent

CA 1157033

Abstract A composition and method for the preparation of a technetium-99m-based scanning agent are disclosed. The scanning agent is prepared from 99mTc, in a +3, +4 and/or +5 oxidation state, and a methanehydroxydiphosphonate bone-seeking agent which carries the radionuclide to bone mineral. The methanehydroxydiphosphonate agent provides scan sharpness equivalent or superior to commerical scanning agents, and is superior to commerical infarcts, as compared with commerical scanning agents such as ethane-1-hydroxy-1,1-diphosphonate and methane- diphosphante.

404910

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