Radiohalogenated compounds for site specific labeling

Details Radiohalogenated compounds for site specific labeling Radiohalogenated compounds for site specific labeling

C - Chemistry, Metallurgy

07

C

167/139, 167/41,

C07C 243/38 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) C07B 59/00 (2006.01)

Patent

CA 1318615

ABSTRACT OF THE DISCLOSURE Radiohalogenated compounds which are useful as intermediates for preparing radiohalogenated antibody conjugates in which the radiohalogenated compound is site specifically attached to an oxidized carbohydrate moiety of an antibody or antibody fragment are disclosed. Methods for making the compounds and the antibody conjugates as well as methods of use of the same are also disclosed.

601795

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