A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/04 (2006.01) C07B 59/00 (2006.01) C07F 9/02 (2006.01) C07F 9/09 (2006.01)
Patent
CA 2276284
Improved radioiodinated phospholipid ether analogs are described which demonstrate significant tumor avidity and longer plasma half-life than shorter-chain analogs, providing superior imaging and visualization of neoplastic lesions and tumor-specific cytotoxic cancer therapy.
L'invention concerne des analogues radio-iodés d'éthers de phospolipidiques qui présentent une importante avidité pour les tumeurs et ont une demi-vie dans le plasma plus longue que les analogues à chaîne plus courte; ils améliorent l'imagerie et le visualisation des lésions néoplasiques et permettent une thérapie cytotoxique du cancer spécifique des tumeurs.
Counsell Raymond E.
Longino Marc A.
Pinchuk Anatoly N.
Rampy Mark A.
Weichert Jamey P.
Smart & Biggar
The Regents Of The University Of Michigan
LandOfFree
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