Radiolabeled anilinoquinazolines and their use in...

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01)

Patent

CA 2538633

Radiolabeled epidermal growth factor receptor tyrosine kinase (EGFR-TK) irreversible inhibitors and their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are disclosed.

L'invention concerne des inhibiteurs irréversibles de la tyrosine kinase du récepteur du facteur de croissance épidermique (EGFR-TK) et leurs utilisations en tant que biomarqueurs en radioimagerie médicale telle que la tomographie par émission de positrons (TEP) et la tomographie monophotonique d'émission (SPECT) et en tant qu'agents radiopharmaceutiques de radiothérapie.

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