Radiolabeled anti-platelet monoclonal antibody for imaging...

Details Radiolabeled anti-platelet monoclonal antibody for imaging... Radiolabeled anti-platelet monoclonal antibody for imaging...

C - Chemistry, Metallurgy

07

K

167/45, 195/1.1

C07K 16/28 (2006.01) A61K 51/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1333264

There is provided a radiolabeled monoclonal antibody of the class IgG1 which reacts readily with both normal human and dog blood platelets while failing to react with thrombasthenic human platelets. This antibody has the property of completely blocking interaction of fibrinogen with platelets induced by ADP, and the ability to detect fresh thrombi in vivo.

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