Radiolabeled dihydrotetrabenazine derivatives and their use...

C - Chemistry – Metallurgy – 07 – D

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C07D 455/06 (2006.01) A61K 51/04 (2006.01) C07D 493/20 (2006.01)

Patent

CA 2650904

This invention relates to a method of imaging vesicular monoamine transporters and to labeled compounds and pharmaceutical compositions thereof, and methods of making labeled compounds useful in imaging vesicular monoamine transporters. This invention also relates to compounds, and methods of monitoring progression of a disease related to vesicular monoamine transporters.

L'invention porte sur un procédé qui permet de former l'image des transporteurs vésiculaires des monoamines, sur des composés marqués et des compositions pharmaceutiques les renfermant, et sur des procédés de fabrication de composés marqués utilisés pour former l'image des transporteurs vésiculaires des monoamines. L'invention concerne également des composés et des procédés qui permettent de surveiller la progression d'une maladie liée aux transporteurs vésiculaires des monoamines.

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