Radiolabeled gallium complexes, methods for synthesis and...

Details Radiolabeled gallium complexes, methods for synthesis and... Radiolabeled gallium complexes, methods for synthesis and...

A - Human Necessities

61

K

A61K 51/08 (2006.01)

Patent

CA 2598863

Methods for labeling synthesis of radiolabeled gallium complex by microwave activation are provided. The resultant gallium-isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). A method for imaging EGFR overexpression in tumors using PET is also provided.

L'invention concerne des méthodes de synthèse par marquage d'un complexe de gallium radiomarqué par activation par hyperfréquences. Les composés marqués à l'isotope de gallium résultants sont utiles en tant qu'agents radiopharmaceutiques notamment pour une utilisation en tomographie par émission de positrons (TEP). L'invention concerne également un procédé d'imagerie de la surexpression du récepteur du facteur de croissance épidermique (EGF) dans des tumeurs par TEP.

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