C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/94 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01) A61N 5/00 (2006.01) C07B 59/00 (2006.01) A61B 6/03 (2006.01)
Patent
CA 2440552
Radiolabeled epidermal growth factor receptor tyrosine kinase (EGFR-TK) irreversible inhibitors and their use as biomarkers for medicinal radioimaging such as Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) and as radiopharmaceuticals for radiotherapy are disclosed.
L'invention concerne des inhibiteurs irréversibles de l'activité tyrosine kinase du récepteur du facteur de croissance épidermique radiomarqués (EGFR-TK) et leur utilisation en tant que biomarqueurs dans la radio-imagerie médicinale, telle que la tomographie par émission de positons (TEP) et la tomographie informatisée par émission de photons uniques (TEM) et en tant que produits radiopharmaceutiques dans la radiothérapie.
Ben-David Iris
Levitzki Alexander
Mishani Eyal
Ortu Giuseppina
Rozen Yulia
Hadasit Medical Research Services And Development Ltd.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Yissum Research Development Company Of The Hebrew University In
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