Radiolabeling kit and binding assay

Details Radiolabeling kit and binding assay Radiolabeling kit and binding assay

G - Physics

01

N

G01N 33/534 (2006.01) A61K 51/10 (2006.01)

Patent

CA 2362119

Antibody binding assays and radiolabeling kits are disclosed for radiolabeling and testing therapeutic antibodies in the commercial setting. In particular, the kits are designed for making and evaluating radiolabeled anti-CD20 conjugates to be used for the treatment and imaging of B cell lymphoma tumors. All kit reagents are sterile and are designed to achieve a high level of antibody radiolabeling and product stability with results which are highly reproducible.

L'invention concerne des systèmes d'immunodétection et des kits de marquage isotopique d'anticorps permettant de marquer isotopiquement et d'analyser des anticorps thérapeutiques dans un cadre commercial. Ces kits sont plus particulièrement conçus pour élaborer et évaluer des conjugués anti-CD20 marqués isotopiquement et destinés à être utilisés pour traiter et visualiser des tumeurs à lymphome malin à cellules B. Tous les réactifs de ce kit sont stériles et aptes à produire un niveau élevé de marquage isotopique d'anticorps et de stabilité du produit, avec des résultats largement reproductibles.

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