Radiolabelled compound formulations

C - Chemistry – Metallurgy – 07 – B

Patent

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Details

C07B 59/00 (2006.01) A61K 51/04 (2006.01) A61K 51/12 (2006.01) C07B 63/04 (2006.01) C07C 227/44 (2006.01) C07C 319/26 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2105402

Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabiliser and dye.

Cette invention concerne des additifs qui sont proposés pour des compositions renfermant des composés organiques marqués isotopiquement tels que des nucléotides marqués 32P. Des stabilisateurs sont sélectionnés parmi le tryptophane, le para-aminobenzoate, l'indoleacétate et le groupe azole. Des colorants sont sélectionnés parmi la sulforhodamine B, le cyanol de xylène, l'azocarmine B et la nouvelle coccine. Les compositions préférées contiennent un tel stabilisateur et un tel colorant.

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